Mathematics plays an essential role in economics because many ideas, relationships and definitions are expressed in formulas. However, students of economics are, frequently, reluctant to study it, which affects their learning. This resistance could be due to the teacher’s lack of ability, not enough interest of the student, or simply fear. The aim of this research is to assess anxiety toward the mathematics of the students of the Faculty of Economics at the Universidad Autonoma de San Luis Potosi (UASLP) in Mexico. This study is non-experimental, cross-sectional and exploratory factorial. The sample comprises the college students majoring in economics at UASLP that were taking math courses in 2015. Auzmendi’s (1992) questionnaire on anxiety and attitude toward mathematics is administered to them. The main empirical finding is that students of economics at UASLP do develop anxiety toward mathematics.